Pseudomonas aeruginosa PAO1, PA2509 (catB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2509
Name
catB
Replicon chromosome
Genomic location 2825958 - 2827079 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_251199.1
GI 15597705
Affymetrix PA2509_catB_at
DNASU PaCD00007090
Entrez 882968
GenBank AAG05897.1
INSDC AAG05897.1
NCBI Locus Tag PA2509
protein_id(GenBank) gb|AAG05897.1|AE004678_3|gnl|PseudoCAP|PA2509
TIGR NTL03PA02509
UniParc UPI00000C5712
UniProtKB Acc Q9I0X3
UniProtKB ID Q9I0X3_PSEAE
UniRef100 UniRef100_Q9I0X3
UniRef50 UniRef50_G8Q216
UniRef90 UniRef90_V6AFC2

Product

Feature Type CDS
Coding Frame 1
Product Name
muconate cycloisomerase I
Product Name Confidence: Class 2
Synonyms cis-muconate lactonizing enzyme I
cis
Evidence for Translation
Charge (pH 7) -0.44
Kyte-Doolittle Hydrophobicity Value -0.035
Molecular Weight (kDa) 40.0
Isoelectric Point (pI) 6.94

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 380 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003051 (464 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2509
Search term: catB

Human Homologs

References

Cloning and complete nucleotide sequence determination of the catB gene encoding cis,cis-muconate lactonizing enzyme.
Aldrich TL, Frantz B, Gill JF, Kilbane JJ, Chakrabarty AM
Gene 1987;52(2-3):185-95
PubMed ID: 3609743
Crystal structure of muconate lactonizing enzyme at 3 A resolution.
Goldman A, Ollis DL, Steitz TA
J Mol Biol 1987 Mar 5;194(1):143-53
PubMed ID: 3612800