Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2528
|
Name |
muxA
Synonym: yegM |
Replicon | chromosome |
Genomic location | 2854011 - 2855291 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_251218.1 |
GI | 15597724 |
Affymetrix | PA2528_at |
Entrez | 882937 |
GenBank | AAG05916.1 |
INSDC | AAG05916.1 |
NCBI Locus Tag | PA2528 |
protein_id(GenBank) | gb|AAG05916.1|AE004680_4|gnl|PseudoCAP|PA2528 |
TIGR | NTL03PA02528 |
UniParc | UPI00000C571F |
UniProtKB Acc | Q9I0V5 |
UniProtKB ID | Q9I0V5_PSEAE |
UniRef100 | UniRef100_A0A069QB48 |
UniRef50 | UniRef50_Q48IF0 |
UniRef90 | UniRef90_W0YTB6 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
MuxA
|
Synonyms |
probable RND efflux membrane fusion protein precursor |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 3.25 |
Kyte-Doolittle Hydrophobicity Value | -0.184 |
Molecular Weight (kDa) | 45.3 |
Isoelectric Point (pI) | 9.52 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
MuxA | MuxA is a membrane fusion protein component of the efflux pump system MuxABC-OpmB in Pseudomonas aeruginosa. [PMID:19713238] | ARO:3004073 | protein homolog model | Perfect | 803.1 | 100.0 | 3.2.5 |
Source 1 | |
Database | PseudoCAP |
Category | |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | Drosophila melanogaster |
Notes | |
Infection model | Drosophila melanogaster infection |
Reference | 21369987 |
Source 2 | |
Database | PseudoCAP |
Category | |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | Brassica pekinensis |
Notes | |
Infection model | Brassica pekinensis infection |
Reference | 21369987 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 433 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003039 (534 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2528
Search term: muxA
Search term: MuxA
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa.
Mima T, Kohira N, Li Y, Sekiya H, Ogawa W, Kuroda T, Tsuchiya T
Microbiology (Reading) 2009 Nov;155(Pt 11):3509-3517
PubMed ID: 19713238
|