Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2873
|
Name |
tgpA
|
Replicon | chromosome |
Genomic location | 3225381 - 3227387 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
Comment | TgpA plays a critical role in the viability of P. aeruginosa. |
RefSeq | NP_251563.1 |
GI | 15598069 |
Affymetrix | PA2873_at |
Entrez | 882644 |
GenBank | AAG06261.1 |
INSDC | AAG06261.1 |
NCBI Locus Tag | PA2873 |
protein_id(GenBank) | gb|AAG06261.1|AE004713_10|gnl|PseudoCAP|PA2873 |
TIGR | NTL03PA02873 |
UniParc | UPI00000C5855 |
UniProtKB Acc | Q9HZX3 |
UniProtKB ID | TGPA_PSEAE |
UniRef100 | UniRef100_Q9HZX3 |
UniRef50 | UniRef50_Q9HZX3 |
UniRef90 | UniRef90_Q9HZX3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
transglutaminase protein A, TgpA
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 16.60 |
Kyte-Doolittle Hydrophobicity Value | 0.015 |
Molecular Weight (kDa) | 74.8 |
Isoelectric Point (pI) | 10.11 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6G49 | TRANSFERASE | 03/27/18 | Crystal structure of the periplasmic domain of TgpA from Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 1.6 | X-RAY DIFFRACTION | 100.0 |
6G4H | TRANSFERASE | 03/27/18 | Crystal structure of the periplasmic domain of TgpA from Pseudomonas aeruginosa bound to ethylmercury | Pseudomonas aeruginosa PAO1 | 1.8 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 289 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002698 (1284 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2873
Search term: tgpA
Search term: transglutaminase protein A, TgpA
|
TgpA, a protein with a eukaryotic-like transglutaminase domain, plays a critical role in the viability of Pseudomonas aeruginosa.
Milani A, Vecchietti D, Rusmini R, Bertoni G
PLoS One 2012;7(11):e50323
PubMed ID: 23209712
|