Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3485
|
Name |
tsi3
|
Replicon | chromosome |
Genomic location | 3899501 - 3899938 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
RefSeq | NP_252175.1 |
GI | 15598681 |
Affymetrix | PA3485_r_at |
DNASU | PaCD00007532 |
Entrez | 879938 |
GenBank | AAG06873.1 |
INSDC | AAG06873.1 |
NCBI Locus Tag | PA3485 |
protein_id(GenBank) | gb|AAG06873.1|AE004769_6|gnl|PseudoCAP|PA3485 |
TIGR | NTL03PA03485 |
UniParc | UPI00000C5A33 |
UniProtKB Acc | Q9HYC4 |
UniProtKB ID | Q9HYC4_PSEAE |
UniRef100 | UniRef100_W0YWF6 |
UniRef50 | UniRef50_A6V1U0 |
UniRef90 | UniRef90_Q02QX4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Tsi3
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -3.79 |
Kyte-Doolittle Hydrophobicity Value | -0.443 |
Molecular Weight (kDa) | 15.8 |
Isoelectric Point (pI) | 4.85 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4M5F | HYDROLASE INHIBITOR | 08/08/13 | complex structure of Tse3-Tsi3 | Pseudomonas aeruginosa | 2.5 | X-RAY DIFFRACTION | 100.0 |
8IK0 | IMMUNE SYSTEM | 02/28/23 | Cryo-EM structure of Stimulator of interferon genes | Gallus gallus; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 3.3 | ELECTRON MICROSCOPY | 100.0 |
4N88 | HYDROLASE/HYDROLASE INHIBITOR | 10/17/13 | Crystal structure of Tse3-Tsi3 complex with calcium ion | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 100.0 |
4N80 | HYDROLASE/HYDROLASE INHIBITOR | 10/16/13 | Crystal structure of Tse3-Tsi3 complex | Pseudomonas aeruginosa | 2.4 | X-RAY DIFFRACTION | 98.4 |
8IK3 | IMMUNE SYSTEM | 02/28/23 | Structure of Stimulator of interferon genes/ligand complex | Homo sapiens | 3.3 | ELECTRON MICROSCOPY | 100.0 |
4LUQ | PROTEIN BINDING/TOXIN INHIBITOR | 07/25/13 | Crystal structure of virulence effector Tse3 in complex with neutralizer Tsi3 | Pseudomonas aeruginosa | 1.77 | X-RAY DIFFRACTION | 98.4 |
3WA5 | HYDROLASE | 04/26/13 | Crystal Structure of type VI peptidoglycan muramidase effector Tse3 in complex with its cognate immunity protein Tsi3 | Pseudomonas aeruginosa | 1.9 | X-RAY DIFFRACTION | 100.0 |
4N7S | HYDROLASE/HYDROLASE INHIBITOR | 10/16/13 | Crystal structure of Tse3-Tsi3 complex with Zinc ion | Pseudomonas aeruginosa | 2.101 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in one genus
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002157 (299 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3485
Search term: tsi3
Search term: Tsi3
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Type VI secretion delivers bacteriolytic effectors to target cells.
Russell AB, Hood RD, Bui NK, LeRoux M, Vollmer W, Mougous JD
Nature 2011 Jul 20;475(7356):343-7
PubMed ID: 21776080
|