Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4460
|
Name |
lptH
Synonym: yhbN |
Replicon | chromosome |
Genomic location | 4991392 - 4991919 (+ strand) |
RefSeq | NP_253150.1 |
GI | 15599656 |
Affymetrix | PA4460_at |
DNASU | PaCD00007934 |
Entrez | 881017 |
GenBank | AAG07848.1 |
INSDC | AAG07848.1 |
NCBI Locus Tag | PA4460 |
protein_id(GenBank) | gb|AAG07848.1|AE004860_4|gnl|PseudoCAP|PA4460 |
TIGR | NTL03PA04461 |
UniParc | UPI00000C5D1F |
UniProtKB Acc | Q9HVV7 |
UniProtKB ID | Q9HVV7_PSEAE |
UniRef100 | UniRef100_W0YZJ5 |
UniRef50 | UniRef50_A6VBD4 |
UniRef90 | UniRef90_A6VBD4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
LptH
|
Synonyms | |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 2.99 |
Kyte-Doolittle Hydrophobicity Value | -0.358 |
Molecular Weight (kDa) | 19.1 |
Isoelectric Point (pI) | 9.57 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4UU4 | TRANSPORT PROTEIN | 07/24/14 | Crystal structure of LptH, the LptA homologous periplasmic component of the conserved lipopolysaccharide transport device from Pseudomonas aeruginosa | PSEUDOMONAS AERUGINOSA | 2.751 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 131 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004049 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4460
Search term: lptH
Search term: LptH
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Crystal structure of LptH, the periplasmic component of the lipopolysaccharide transport machinery from Pseudomonas aeruginosa.
Bollati M, Villa R, Gourlay LJ, Benedet M, Dehò G, Polissi A, Barbiroli A, Martorana AM, Sperandeo P, Bolognesi M, Nardini M
FEBS J 2015 May;282(10):1980-97
PubMed ID: 25735820
|
Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli.
Okuda S, Freinkman E, Kahne D
Science 2012 Nov 30;338(6111):1214-7
PubMed ID: 23138981
|