Pseudomonas aeruginosa PAO1, PA4490 (magC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4490
Name
magC
Replicon chromosome
Genomic location 5024979 - 5025617 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253180.1
GI 15599686
Affymetrix PA4490_at
DNASU PaCD00007944
Entrez 881073
GenBank AAG07878.1
INSDC AAG07878.1
NCBI Locus Tag PA4490
protein_id(GenBank) gb|AAG07878.1|AE004862_12|gnl|PseudoCAP|PA4490
TIGR NTL03PA04491
UniParc UPI0000139DE2
UniProtKB Acc Q9HVT1
UniProtKB ID Y4490_PSEAE
UniRef100 UniRef100_Q9HVT1
UniRef50 UniRef50_P76466
UniRef90 UniRef90_Q9HVT1

Product

Feature Type CDS
Coding Frame 1
Product Name
MagC
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.92
Kyte-Doolittle Hydrophobicity Value -0.421
Molecular Weight (kDa) 24.0
Isoelectric Point (pI) 10.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7BK8 HYDROLASE 01/15/21 X-ray crystal structure of Pseudomonas aeruginosa MagC Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.74 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 17 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004078 (358 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4490
Search term: magC
Search term: MagC

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Unique features of a Pseudomonas aeruginosa α2-macroglobulin homolog.
Robert-Genthon M, Casabona MG, Neves D, Couté Y, Cicéron F, Elsen S, Dessen A, Attrée I
MBio 2013 Aug;4(4):
PubMed ID: 23919994