Pseudomonas aeruginosa PAO1, PA4492 (magA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4492
Name
magA
Replicon chromosome
Genomic location 5027422 - 5028231 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253182.1
GI 15599688
Affymetrix PA4492_at
DNASU PaCD00007945
Entrez 881055
GenBank AAG07880.1
INSDC AAG07880.1
NCBI Locus Tag PA4492
protein_id(GenBank) gb|AAG07880.1|AE004862_14|gnl|PseudoCAP|PA4492
TIGR NTL03PA04493
UniParc UPI00000C5D34
UniProtKB Acc Q9HVS9
UniProtKB ID Q9HVS9_PSEAE
UniRef100 UniRef100_Q9HVS9
UniRef50 UniRef50_Q9HVS9
UniRef90 UniRef90_Q9HVS9

Product

Feature Type CDS
Coding Frame 1
Product Name
MagA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.36
Kyte-Doolittle Hydrophobicity Value -0.242
Molecular Weight (kDa) 29.3
Isoelectric Point (pI) 6.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Membrane Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 22 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004080 (358 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4492
Search term: magA
Search term: MagA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Unique features of a Pseudomonas aeruginosa α2-macroglobulin homolog.
Robert-Genthon M, Casabona MG, Neves D, Couté Y, Cicéron F, Elsen S, Dessen A, Attrée I
MBio 2013 Aug;4(4):
PubMed ID: 23919994