Pseudomonas aeruginosa PAO1, PA4624 (cdrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA4624
Name
cdrB
Replicon chromosome
Genomic location 5184642 - 5186348 (- strand)
Transposon Mutants 12 transposon mutants in PAO1
Transposon Mutants in orthologs 8 transposon mutants in orthologs

Cross-References

RefSeq NP_253314.1
GI 15599820
Affymetrix PA4624_at
Entrez 881173
GenBank AAG08012.1
INSDC AAG08012.1
NCBI Locus Tag PA4624
protein_id(GenBank) gb|AAG08012.1|AE004876_7|gnl|PseudoCAP|PA4624
TIGR NTL03PA04625
UniParc UPI00000C5D94
UniProtKB Acc Q9HVG7
UniProtKB ID Q9HVG7_PSEAE
UniRef100 UniRef100_Q9HVG7
UniRef50 UniRef50_Q9HVG7
UniRef90 UniRef90_Q9HVG7

Product

Feature Type CDS
Coding Frame 1
Product Name
cyclic diguanylate-regulated TPS partner B, CdrB
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) -5.83
Kyte-Doolittle Hydrophobicity Value -0.409
Molecular Weight (kDa) 63.3
Isoelectric Point (pI) 5.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 152 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000040 (1642 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4624
Search term: cdrB

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.
Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb JF, Dougherty BA, Merrick JM
Science 1995 Jul;269(5223):496-512
PubMed ID: 7542800
Pseudomonas aeruginosa uses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix.
Borlee BR, Goldman AD, Murakami K, Samudrala R, Wozniak DJ, Parsek MR
Mol. Microbiol. 2010 Feb;75(4):827-42
PubMed ID: 20088866
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994