Pseudomonas fluorescens Pf0-1, Pfl01_1789 (gcbB)

Gene Feature Overview

Strain	Pseudomonas fluorescens Pf0-1 GCF_000012445.1|latest
Locus Tag	Pfl01_1789
Name	gcbB
Replicon	chromosome
Genomic location	1991939 - 1994323 (+ strand)

Cross-References

RefSeq	YP_347521.1
GI	77458016
Entrez	3716587
INSDC	ABA73532.1
NCBI Locus Tag	Pfl01_1789
UniParc	UPI00003C754F
UniProtKB Acc	Q3KFC4
UniProtKB ID	Q3KFC4_PSEPF
UniRef100	UniRef100_Q3KFC4
UniRef50	UniRef50_Q4KFI5
UniRef90	UniRef90_Q3KFC4

Product

Feature Type	CDS
Coding Frame	1
Product Name	GcbB Product Name Confidence: Class 1
Synonyms	PAS/PAC sensor-containing diguanylate cyclase
Evidence for Translation
Charge (pH 7)	-10.36
Kyte-Doolittle Hydrophobicity Value	-0.182
Molecular Weight (kDa)	88986.5
Isoelectric Point (pI)	6.34

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG015570 (153 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: Pfl01_1789 Search term: gcbB Search term: GcbB

Human Homologs

References

Systematic analysis of diguanylate cyclases that promote biofilm formation by Pseudomonas fluorescens Pf0-1. Newell PD, Yoshioka S, Hvorecny KL, Monds RD, O'Toole GA J Bacteriol 2011 Sep;193(18):4685-98 PubMed ID: 21764921