Pseudomonas aeruginosa UCBPP-PA14, PA14_17380 (gfnR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_17380
Name
gfnR
Replicon chromosome
Genomic location 1491983 - 1492891 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_789534.1
GI 116051627
Entrez 4381593
INSDC ABJ12863.1
NCBI Locus Tag PA14_17380
UniParc UPI0000396123
UniProtKB Acc Q02RA2
UniProtKB ID Q02RA2_PSEAB
UniRef100 UniRef100_S0HTI0
UniRef50 UniRef50_A9L4A5
UniRef90 UniRef90_Q9HY00

Product

Feature Type CDS
Coding Frame 1
Product Name
glutathione-dependent formaldehyde neutralization regulator GfnR
Product Name Confidence: Class 1
Synonyms LysR family transcriptional regulator
Evidence for Translation
Charge (pH 7) 3.98
Kyte-Doolittle Hydrophobicity Value -0.355
Molecular Weight (kDa) 34.2
Isoelectric Point (pI) 8.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 491 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002044 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_17380
Search term: gfnR

Human Homologs

References

Sarcosine Catabolism in Pseudomonas aeruginosa Is Transcriptionally Regulated by SouR.
Willsey GG, Wargo MJ
J Bacteriol 2016 Jan 15;198(2):301-10
PubMed ID: 26503852