Pseudomonas aeruginosa UCBPP-PA14, PA14_58470 (dppD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_58470
Name
dppD
Replicon chromosome
Genomic location 5207642 - 5208616 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_792850.1
GI 116052536
Entrez 4382626
INSDC ABJ13772.1
NCBI Locus Tag PA14_58470
UniParc UPI00003963B2
UniProtKB Acc Q02GT6
UniProtKB ID Q02GT6_PSEAB
UniRef100 UniRef100_A0A069PYH4
UniRef50 UniRef50_Q4KIC6
UniRef90 UniRef90_A0A069PYH4

Product

Feature Type CDS
Coding Frame 1
Product Name
dipeptide ABC transporter ATP-binding protein DppD
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -5.01
Kyte-Doolittle Hydrophobicity Value 0.052
Molecular Weight (kDa) 35.4
Isoelectric Point (pI) 6.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004092 (540 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_58470
Search term: dppD

Human Homologs

Ensembl 86, assembly GRCh38.p7
ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40]
E-value: 1.1e-15
Percent Identity: 32.3

Transposon Insertions in UCBPP-PA14

Type MAR2xT7 transposon (wild type background) insertion site
Mutant ID PA14NR: 28820
Genomic Position 5207954
Position in ORF 313(975)
Reference 16477005

Transposon Insertions in Orthologs

Type Confirmed ISphoA/hah insertion site
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA4505
Mutant ID UWGC: 41254
Genomic Position 5044203
Position in ORF 150(975)
Reference 14617778

References

High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa.
Pletzer D(1), Lafon C(2), Braun Y(1), Köhler T(3), Page MG(4), Mourez M(2), Weingart H(1).
PLoS One. 2014 Oct 22;9(10):e111311.
PubMed ID: 25338022