Pseudomonas aeruginosa UCBPP-PA14, PA14_70290 (sphR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_70290
Name
sphR
Replicon chromosome
Genomic location 6267659 - 6268729 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_793798.1
GI 116053471
Entrez 4385087
INSDC ABJ14707.1
NCBI Locus Tag PA14_70290
UniParc UPI000045D56D
UniProtKB Acc Q02E38
UniProtKB ID Q02E38_PSEAB
UniRef100 UniRef100_S0HXE1
UniRef50 UniRef50_Q4KAC5
UniRef90 UniRef90_W0Z282

Product

Feature Type CDS
Coding Frame 1
Product Name
Sphingosine-responsive Regulator, SphR
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 3.77
Kyte-Doolittle Hydrophobicity Value -0.085
Molecular Weight (kDa) 39.8
Isoelectric Point (pI) 8.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 227 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000800 (1527 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_70290
Search term: sphR

Transposon Insertions in UCBPP-PA14

Type MAR2xT7 transposon (wild type background) insertion site
Mutant ID PA14NR: 31020
Genomic Position 6268356
Position in ORF 698(1071)
Reference 16477005

Transposon Insertions in Orthologs

References

Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung.
LaBauve AE, Wargo MJ
PLoS Pathog. 2014 Jan;10(1):e1003889
PubMed ID: 24465209