Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2794
|
Name |
|
Replicon | chromosome |
Genomic location | 3150886 - 3152202 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_251484 |
GI | 15597990 |
Affymetrix | PA2794_at |
GenBank | AAG06182.1 |
protein_id(GenBank) | gb|AAG06182.1|AE004707_1|gnl|PseudoCAP|PA2794 |
TIGR | NTL03PA02794 |
UniProtKB Acc | Q9L6G4 |
UniProtKB ID | Q9L6G4_PSEAE |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
pseudaminidase
|
Synonyms |
PaNA |
Evidence for Translation | |
Charge (pH 7) | -3.88 |
Kyte-Doolittle Hydrophobicity Value | -0.144 |
Molecular Weight (kDa) | 47.2 |
Isoelectric Point (pI) | 6.24 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2W38 | TRANSFERASE | 11/07/08 | Crystal structure of the pseudaminidase from Pseudomonas aeruginosa | PSEUDOMONAS AERUGINOSA | 1.9 | X-RAY DIFFRACTION | 100.0 |
3H6J | HYDROLASE | 04/23/09 | Crystal structure of a putative neuraminidase from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 1.6 | X-RAY DIFFRACTION | 99.3 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002775 (91 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2794
Search term: pseudaminidase
|
Structural studies on the Pseudomonas aeruginosa sialidase-like enzyme PA2794 suggest substrate and mechanistic variations.
Xu G, Ryan C, Kiefel MJ, Wilson JC, Taylor GL
J Mol Biol 2009 Feb 27;386(3):828-40
PubMed ID: 19166860
|
Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production.
Soong G, Muir A, Gomez MI, Waks J, Reddy B, Planet P, Singh PK, Kaneko Y, Wolfgang MC, Hsiao YS, Tong L, Prince A
J Clin Invest 2006 Aug;116(8):2297-2305
PubMed ID: 16862214
|