Pseudomonas aeruginosa PAO1, PA0259 (tla3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Annotation Updates

Date Description Acknowledgements
Sep 15, 2020 New comment: In a previous release, we updated the start site to 291154 based on a recombinant tla3 gene with this start site being used in E. coli. There is no evidence for 291154 being the translation initiation site in P. aeruginosa so it have been reverted back to 291004. Sophie Bleves, Institute of Microbiology of the Mediterranean, France
Oct 9, 2019 New gene name: tla3. New product name: Type 6 lipase adaptor, Tla3. New product name confidence: Class 1. New comment: Translation start site moved to position 291154 based on upstream ribosome bindng site and significant Kolaskar score (PMID: 31231326).;Tla3 is localized in the cytoplasm of P. aeruginosa and is required for Tle3 secretion and antibacterial activity in P. aeruginosa. Direct interaction with Tle3 and VgrG2b. New PMID: 31231326. Sophie Bleves, Institute of Microbiology of the Mediterranean, France
Nov 24, 2014 New gene name: tli3. New product name name: Tli3. New product name confidence: Class 2. New PubMed ID: 23552891. New PseudoCAP function class: Adaptation, Protection. John Whitney, University of Washington School of Medicine, USA