Pseudomonas aeruginosa PAO1, PA3807 (ndk)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004766	spermidine synthase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0004550	nucleoside diphosphate kinase activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	8809750	Reviewed by curator
Biological Process	GO:0042121	alginic acid biosynthetic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	8809750	Reviewed by curator
Biological Process	GO:0006220	pyrimidine nucleotide metabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	8809750	Reviewed by curator
Biological Process	GO:0006163	purine nucleotide metabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	8809750	Reviewed by curator
Biological Process	GO:0009117	nucleotide metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006228	UTP biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00451	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004550	nucleoside diphosphate kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00451	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006241	CTP biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00451	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006183	GTP biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00451	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae00230	Purine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00240	Pyrimidine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	PPGPPMET-PWY	ppGpp biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCAP		Pyrimidine metabolism		ECO:0000037 not_recorded
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Purine metabolism		ECO:0000037 not_recorded
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	PWY-7221	guanosine ribonucleotides de novo biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Hamap	MF_00451	Nucleoside diphosphate kinase [ndk].	IPR001564	Nucleoside diphosphate kinase	3	138	36.435814
PRINTS	PR01243	Nucleoside diphosphate kinase signature	IPR001564	Nucleoside diphosphate kinase	114	133	3.8E-41
PRINTS	PR01243	Nucleoside diphosphate kinase signature	IPR001564	Nucleoside diphosphate kinase	6	28	3.8E-41
SUPERFAMILY	SSF54919	Nucleoside diphosphate kinase, NDK	IPR036850	Nucleoside diphosphate kinase-like domain superfamily	1	140	6.29E-59
PRINTS	PR01243	Nucleoside diphosphate kinase signature	IPR001564	Nucleoside diphosphate kinase	91	107	3.8E-41
PRINTS	PR01243	Nucleoside diphosphate kinase signature	IPR001564	Nucleoside diphosphate kinase	70	87	3.8E-41
FunFam	G3DSA:3.30.70.141:FF:000001	Nucleoside diphosphate kinase	-	-	1	139	7.6E-76
Gene3D	G3DSA:3.30.70.141	-	IPR036850	Nucleoside diphosphate kinase-like domain superfamily	1	140	1.0E-58
PANTHER	PTHR46161	NUCLEOSIDE DIPHOSPHATE KINASE	-	-	2	134	3.9E-47
CDD	cd04413	NDPk_I	-	-	4	133	1.17666E-83
PRINTS	PR01243	Nucleoside diphosphate kinase signature	IPR001564	Nucleoside diphosphate kinase	50	69	3.8E-41
Pfam	PF00334	Nucleoside diphosphate kinase	IPR034907	Nucleoside diphosphate kinase-like domain	4	137	3.4E-58
SMART	SM00562	ndk_5	IPR034907	Nucleoside diphosphate kinase-like domain	3	140	1.8E-91

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.