Pseudomonas aeruginosa PAO1, PA3976 (thiE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051188 obsolete cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009228 thiamine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8432721 Reviewed by curator
Molecular Function GO:0004789 thiamine-phosphate diphosphorylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00693
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009228 thiamine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00693
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00730 Thiamine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.20.20.70:FF:000276 Thiamine-phosphate synthase - - 1 207 0.0
NCBIfam TIGR00693 JCVI: thiamine phosphate synthase IPR034291 Thiamine phosphate synthase 6 197 5.0E-60
Hamap MF_00097 Thiamine-phosphate synthase [thiE]. IPR034291 Thiamine phosphate synthase 4 207 24.907307
Pfam PF02581 Thiamine monophosphate synthase IPR022998 Thiamine phosphate synthase/TenI 6 186 6.7E-54
PANTHER PTHR20857 THIAMINE-PHOSPHATE PYROPHOSPHORYLASE - - 5 201 1.5E-46
SUPERFAMILY SSF51391 Thiamin phosphate synthase IPR036206 Thiamin phosphate synthase superfamily 3 200 1.23E-57
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 1 207 3.7E-57
CDD cd00564 TMP_TenI IPR022998 Thiamine phosphate synthase/TenI 6 183 7.65273E-65

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.