Pseudomonas aeruginosa PAO1, PA4109 (ampR)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:1900232	negative regulation of single-species biofilm formation on inanimate substrate	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	22479525	Reviewed by curator
Biological Process	GO:0050714	positive regulation of protein secretion	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	22479525	Reviewed by curator
Biological Process	GO:1900378	positive regulation of secondary metabolite biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	22479525	Reviewed by curator
Biological Process	GO:0006355	regulation of transcription, DNA-templated	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	22479525	Reviewed by curator
Biological Process	GO:0045862	positive regulation of proteolysis	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	22479525	Reviewed by curator
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00126	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00126	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Antibiotic resistance and susceptibility Other PAO1 genes in this class Transcriptional regulators Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01501	beta-Lactam resistance	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00039	LysR bacterial regulatory protein HTH signature	IPR000847	Transcription regulator HTH, LysR	44	55	1.9E-9
FunFam	G3DSA:1.10.10.10:FF:000038	Glycine cleavage system transcriptional activator	-	-	6	89	1.6E-32
PRINTS	PR00039	LysR bacterial regulatory protein HTH signature	IPR000847	Transcription regulator HTH, LysR	34	44	1.9E-9
Gene3D	G3DSA:3.40.190.10	-	-	-	98	285	2.2E-63
SUPERFAMILY	SSF53850	Periplasmic binding protein-like II	-	-	85	289	7.6E-34
PRINTS	PR00039	LysR bacterial regulatory protein HTH signature	IPR000847	Transcription regulator HTH, LysR	23	34	1.9E-9
Gene3D	G3DSA:1.10.10.10	-	IPR036388	Winged helix-like DNA-binding domain superfamily	2	87	2.4E-22
SUPERFAMILY	SSF46785	Winged helix DNA-binding domain	IPR036390	Winged helix DNA-binding domain superfamily	2	86	3.87E-22
Gene3D	G3DSA:3.40.190.10	-	-	-	164	259	2.2E-63
Pfam	PF03466	LysR substrate binding domain	IPR005119	LysR, substrate-binding	91	289	8.5E-34
PANTHER	PTHR30537	HTH-TYPE TRANSCRIPTIONAL REGULATOR	-	-	6	289	1.2E-70
CDD	cd08484	PBP2_LTTR_beta_lactamase	IPR037420	HTH-type transcriptional activator AmpR, PBP2	95	285	1.48604E-118
Pfam	PF00126	Bacterial regulatory helix-turn-helix protein, lysR family	IPR000847	Transcription regulator HTH, LysR	8	67	3.7E-20

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.