Pseudomonas aeruginosa PAO1, PA4112

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08447
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00448
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 637 751 5.6E-5
Gene3D G3DSA:3.40.50.2300 - - - 1158 1283 1.6E-34
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1315 1405 2.82497E-11
Pfam PF13426 PAS domain IPR000014 PAS domain 503 613 2.0E-11
Pfam PF00989 PAS fold IPR013767 PAS fold 346 457 7.9E-15
FunFam G3DSA:3.30.565.10:FF:000010 Sensor histidine kinase RcsC - - 828 994 3.3E-52
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 876 991 2.9E-30
Gene3D G3DSA:3.30.450.20 PAS domain - - 625 697 1.4E-16
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1315 1397 3.1E-14
SMART SM00086 pac_2 IPR001610 PAC motif 572 614 5.3E-6
Gene3D G3DSA:3.40.50.2300 - - - 1009 1157 2.9E-28
SMART SM00086 pac_2 IPR001610 PAC motif 418 460 0.0089
SMART SM00091 pas_2 IPR000014 PAS domain 345 411 3.0E-8
SMART SM00086 pac_2 IPR001610 PAC motif 702 744 0.012
CDD cd16922 HATPase_EvgS-ArcB-TorS-like - - 881 990 2.66662E-58
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 917 931 3.4E-14
Coils Coil Coil - - 744 764 -
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 771 825 1.69074E-12
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 764 829 2.1E-18
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 500 620 4.2E-15
CDD cd00130 PAS IPR000014 PAS domain 638 741 4.24398E-9
Pfam PF03924 CHASE domain IPR006189 CHASE domain 80 264 7.1E-45
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 1158 1273 2.6E-33
Gene3D G3DSA:2.10.70.100 - - - 699 743 1.0E-11
PANTHER PTHR45339 HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J - - 1003 1096 0.0
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 935 945 3.4E-14
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 1011 1130 4.1714E-32
CDD cd00130 PAS IPR000014 PAS domain 504 611 2.25699E-11
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 828 996 8.5E-49
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1007 1135 1.71E-27
Pfam PF08447 PAS fold IPR013655 PAS fold-3 649 738 3.6E-17
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 1009 1130 1.5E-22
Gene3D G3DSA:3.30.450.20 PAS domain - - 491 624 2.5E-26
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 1161 1270 9.5E-25
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 611 742 2.97E-19
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1306 1408 4.1E-5
FunFam G3DSA:1.10.287.130:FF:000002 Two-component osmosensing histidine kinase - - 751 830 1.5E-29
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 504 621 6.63E-19
CDD cd00130 PAS IPR000014 PAS domain 354 457 2.47789E-12
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 1012 1129 1.3E-13
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 818 988 1.7E-44
Coils Coil Coil - - 34 54 -
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 952 970 3.4E-14
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1301 1403 2.4E-13
FunFam G3DSA:2.10.70.100:FF:000001 Sensory transduction histidine kinase - - 699 745 4.0E-15
SMART SM00091 pas_2 IPR000014 PAS domain 626 696 0.0014
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 976 989 3.4E-14
Coils Coil Coil - - 460 480 -
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 1160 1273 7.3769E-41
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1256 1378 7.59E-17
Gene3D G3DSA:3.30.450.20 PAS domain - - 334 488 9.0E-27
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1155 1279 9.82E-35
Gene3D G3DSA:1.10.287.130 - - - 744 827 6.7E-28
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 343 466 5.8E-24
Gene3D G3DSA:3.30.450.350 CHASE domain IPR042240 CHASE domain superfamily 81 295 7.0E-39
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 748 830 2.55E-21
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 764 829 2.1E-23
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 344 450 1.31E-21
SMART SM01079 CHASE_2 IPR006189 CHASE domain 77 267 2.5E-60
SMART SM00091 pas_2 IPR000014 PAS domain 491 559 6.2E-5
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 876 992 1.6E-38

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.