Pseudomonas aeruginosa PAO1, PA4123 (hpcC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0015976 carbon utilization
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044248 cellular catabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8550403 Reviewed by curator
Biological Process GO:1901022 4-hydroxyphenylacetate metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8550403 Reviewed by curator
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:1901023 4-hydroxyphenylacetate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02299
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53720
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0018480 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02299
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01220 Degradation of aromatic compounds 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Aromatic compound catabolism ECO:0000037
not_recorded
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00350 Tyrosine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc 3-HYDROXYPHENYLACETATE-DEGRADATION-PWY 4-hydroxyphenylacetate degradation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 13 472 0.0
CDD cd07093 ALDH_F8_HMSADH - - 19 474 0.0
Gene3D G3DSA:3.40.309.10 Aldehyde Dehydrogenase; Chain A, domain 2 IPR016163 Aldehyde dehydrogenase, C-terminal 247 443 0.0
NCBIfam TIGR02299 JCVI: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 2 485 0.0
Gene3D G3DSA:3.40.605.10 Aldehyde Dehydrogenase; Chain A, domain 1 IPR016162 Aldehyde dehydrogenase, N-terminal 14 472 0.0
FunFam G3DSA:3.40.605.10:FF:000001 Aldehyde dehydrogenase 1 - - 12 269 3.5E-85
SUPERFAMILY SSF53720 ALDH-like IPR016161 Aldehyde/histidinol dehydrogenase 2 478 0.0
PANTHER PTHR43720 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE - - 1 479 0.0
FunFam G3DSA:3.40.309.10:FF:000012 Betaine aldehyde dehydrogenase - - 245 441 1.6E-71

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.