Pseudomonas aeruginosa PAO1, PA4209 (phzM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 17253782 Reviewed by curator
Molecular Function GO:0003824 catalytic activity
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0002047 phenazine biosynthetic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0008171 O-methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00891
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008168 methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR43712
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53335
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Phenazine biosynthesis ECO:0000037
not_recorded
PseudoCyc PWY-6666 pyocyanin biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc PWYB-5652 Phenazine biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43712 PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED IPR016461 O-methyltransferase COMT-type 12 330 5.7E-47
Pfam PF00891 O-methyltransferase domain IPR001077 O-methyltransferase domain 115 314 2.3E-28
Pfam PF16864 Dimerisation domain IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain 12 86 1.5E-6
SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily 95 330 1.03E-39
Gene3D G3DSA:1.10.10.10 - IPR036388 Winged helix-like DNA-binding domain superfamily 1 88 1.1E-22
SUPERFAMILY SSF46785 Winged helix DNA-binding domain IPR036390 Winged helix DNA-binding domain superfamily 10 89 5.99E-14
PIRSF PIRSF005739 O-mtase IPR016461 O-methyltransferase COMT-type 1 332 1.7E-37
Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily 89 334 2.7E-66

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.