Pseudomonas aeruginosa UCBPP-PA14, PA14_07130 (tktA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52922
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004802 transketolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00232
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other UCBPP-PA14 genes in this class
Carbon compound catabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00030 Pentose phosphate pathway 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00861 Transket_pyr_3 IPR005475 Transketolase-like, pyrimidine-binding domain 354 525 1.3E-69
Gene3D G3DSA:3.40.50.970 - - - 1 325 0.0
FunFam G3DSA:3.40.50.970:FF:000003 Transketolase - - 326 537 2.1E-91
SUPERFAMILY SSF52922 TK C-terminal domain-like IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 533 664 1.83E-42
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 347 526 1.01E-67
Pfam PF02780 Transketolase, C-terminal domain IPR033248 Transketolase, C-terminal domain 540 655 9.0E-16
FunFam G3DSA:3.40.50.970:FF:000004 Transketolase - - 2 325 0.0
NCBIfam TIGR00232 JCVI: transketolase IPR005478 Transketolase, bacterial-like 6 663 0.0
FunFam G3DSA:3.40.50.920:FF:000003 Transketolase - - 538 664 1.7E-50
CDD cd02012 TPP_TK IPR005474 Transketolase, N-terminal 9 273 0.0
Pfam PF00456 Transketolase, thiamine diphosphate binding domain IPR005474 Transketolase, N-terminal 5 333 0.0
PANTHER PTHR43522 TRANSKETOLASE IPR033247 Transketolase family 2 663 0.0
Gene3D G3DSA:3.40.50.970 - - - 326 537 2.7E-87
Gene3D G3DSA:3.40.50.920 - IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 538 665 5.1E-45
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 5 320 7.23E-122
Pfam PF02779 Transketolase, pyrimidine binding domain IPR005475 Transketolase-like, pyrimidine-binding domain 353 525 6.2E-46
CDD cd07033 TPP_PYR_DXS_TK_like - - 358 520 1.05978E-56

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.