Pseudomonas aeruginosa UCBPP-PA14, PA14_10420 (tyrS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004831 tyrosine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11766
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003723 RNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.10.290.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01040
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01040
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006437 tyrosyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01040
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other UCBPP-PA14 genes in this class
Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 166 181 1.0E-25
Gene3D G3DSA:3.10.290.10 - IPR036986 RNA-binding S4 domain superfamily 333 409 8.5E-12
CDD cd00805 TyrRS_core IPR002307 Tyrosine-tRNA ligase 39 307 1.61809E-100
Pfam PF00579 tRNA synthetases class I (W and Y) IPR002305 Aminoacyl-tRNA synthetase, class Ic 36 325 9.5E-67
Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 8 410 40.345512
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 50 72 1.0E-25
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 9 322 9.64E-88
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 187 209 1.0E-25
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 220 232 1.0E-25
SUPERFAMILY SSF55174 Alpha-L RNA-binding motif - - 306 409 1.18E-9
FunFam G3DSA:1.10.240.10:FF:000001 Tyrosine--tRNA ligase - - 227 328 2.6E-28
NCBIfam TIGR00234 JCVI: tyrosine--tRNA ligase IPR002307 Tyrosine-tRNA ligase 8 409 9.5E-97
PANTHER PTHR11766 TYROSYL-TRNA SYNTHETASE IPR024088 Tyrosine-tRNA ligase, bacterial-type 6 403 1.6E-109
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 2 226 4.2E-82
Gene3D G3DSA:1.10.240.10 - - - 227 332 2.3E-29

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.