Pseudomonas aeruginosa UCBPP-PA14, PA14_11400 (ribD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009231 riboflavin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006769
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00227
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00227
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008835 diaminohydroxyphosphoribosylaminopyrimidine deaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006769
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53927
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Antibiotic resistance and susceptibility Other UCBPP-PA14 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00740 Riboflavin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00227 JCVI: riboflavin-specific deaminase C-terminal domain IPR011549 Riboflavin-specific deaminase, C-terminal 148 367 4.6E-53
Gene3D G3DSA:3.40.430.10 Dihydrofolate Reductase, subunit A IPR024072 Dihydrofolate reductase-like domain superfamily 143 372 2.3E-68
PIRSF PIRSF006769 RibD IPR004794 Riboflavin biosynthesis protein RibD 1 370 4.7E-128
FunFam G3DSA:3.40.140.10:FF:000025 Riboflavin biosynthesis protein RibD - - 2 142 8.5E-68
Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region IPR002125 Cytidine and deoxycytidylate deaminase domain 8 101 1.3E-19
CDD cd01284 Riboflavin_deaminase-reductase - - 9 121 2.16466E-55
SUPERFAMILY SSF53597 Dihydrofolate reductase-like IPR024072 Dihydrofolate reductase-like domain superfamily 147 365 1.11E-55
Gene3D G3DSA:3.40.140.10 Cytidine Deaminase, domain 2 - - 2 142 2.4E-47
NCBIfam TIGR00326 JCVI: bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD IPR004794 Riboflavin biosynthesis protein RibD 9 364 5.0E-116
Pfam PF01872 RibD C-terminal domain IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal 149 363 3.3E-47
SUPERFAMILY SSF53927 Cytidine deaminase-like IPR016193 Cytidine deaminase-like 5 146 7.03E-49
PANTHER PTHR38011 DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820) - - 142 366 2.2E-33

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.