Pseudomonas aeruginosa UCBPP-PA14, PA14_11510 (ribA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009231 riboflavin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00505
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003935 GTP cyclohydrolase II activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00505
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00740 Riboflavin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP biosynthesis of riboflavin ECO:0000037
not_recorded
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00925 GTP cyclohydrolase II IPR032677 GTP cyclohydrolase II 8 170 5.8E-67
CDD cd00641 GTP_cyclohydro2 IPR000926 GTP cyclohydrolase II, RibA 2 194 5.45467E-115
NCBIfam TIGR00505 JCVI: GTP cyclohydrolase II IPR000926 GTP cyclohydrolase II, RibA 7 194 5.3E-80
Gene3D G3DSA:3.40.50.10990 GTP cyclohydrolase II IPR036144 GTP cyclohydrolase II superfamily 2 172 7.8E-72
FunFam G3DSA:3.40.50.10990:FF:000002 GTP cyclohydrolase-2 - - 1 174 5.6E-85
SUPERFAMILY SSF142695 RibA-like IPR036144 GTP cyclohydrolase II superfamily 3 172 1.57E-65
PANTHER PTHR21327 GTP CYCLOHYDROLASE II-RELATED - - 3 195 2.3E-80
Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. IPR000926 GTP cyclohydrolase II, RibA 1 196 45.246422

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.