Pseudomonas aeruginosa UCBPP-PA14, PA14_11550 (dxs)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00204
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52922
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016114 terpenoid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00204
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00730 Thiamine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00900 Terpenoid backbone biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd07033 TPP_PYR_DXS_TK_like - - 329 482 4.33512E-69
NCBIfam TIGR00204 JCVI: 1-deoxy-D-xylulose-5-phosphate synthase IPR005477 Deoxyxylulose-5-phosphate synthase 22 624 0.0
Gene3D G3DSA:3.40.50.970 - - - 323 491 4.2E-54
Gene3D G3DSA:3.40.50.970 - - - 11 298 8.3E-83
SMART SM00861 Transket_pyr_3 IPR005475 Transketolase-like, pyrimidine-binding domain 324 488 8.8E-63
FunFam G3DSA:3.40.50.920:FF:000002 1-deoxy-D-xylulose-5-phosphate synthase - - 500 625 6.5E-44
Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase IPR005477 Deoxyxylulose-5-phosphate synthase 18 289 2.3E-121
Gene3D G3DSA:3.40.50.920 - IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 500 625 6.4E-37
CDD cd02007 TPP_DXS IPR005477 Deoxyxylulose-5-phosphate synthase 54 295 5.54859E-123
Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. IPR005477 Deoxyxylulose-5-phosphate synthase 17 625 46.223408
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 15 386 7.41E-77
Pfam PF02780 Transketolase, C-terminal domain IPR033248 Transketolase, C-terminal domain 500 616 4.1E-27
PANTHER PTHR43322 1-D-DEOXYXYLULOSE 5-PHOSPHATE SYNTHASE-RELATED IPR005477 Deoxyxylulose-5-phosphate synthase 9 626 0.0
FunFam G3DSA:3.40.50.970:FF:000005 1-deoxy-D-xylulose-5-phosphate synthase - - 323 490 1.3E-79
Pfam PF02779 Transketolase, pyrimidine binding domain IPR005475 Transketolase-like, pyrimidine-binding domain 325 485 1.9E-36
SUPERFAMILY SSF52922 TK C-terminal domain-like IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 496 625 2.62E-33
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 321 508 1.23E-56

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.