Pseudomonas aeruginosa UCBPP-PA14, PA14_14730 (iscS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0031071 cysteine desulfurase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00331
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0044571 [2Fe-2S] cluster assembly
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00331
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00331
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau04122 Sulfur relay system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00730 Thiamine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 16 263 0.0
NCBIfam TIGR02006 JCVI: IscS subfamily cysteine desulfurase IPR010240 Cysteine desulfurase IscS 1 404 0.0
PANTHER PTHR11601 CYSTEINE DESULFURYLASE FAMILY MEMBER - - 3 384 0.0
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 5 368 0.0
PIRSF PIRSF005572 NifS IPR016454 Cysteine desulfurase 2 384 0.0
Hamap MF_00331 Cysteine desulfurase IscS [iscS]. IPR010240 Cysteine desulfurase IscS 1 395 53.60817
FunFam G3DSA:3.90.1150.10:FF:000002 Cysteine desulfurase IscS - - 257 368 4.5E-50
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 5 391 6.12E-111
FunFam G3DSA:3.40.640.10:FF:000003 Cysteine desulfurase IscS - - 16 263 1.0E-130
Pfam PF00266 Aminotransferase class-V IPR000192 Aminotransferase class V domain 5 368 4.2E-85

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.