Pseudomonas aeruginosa PAO1, PA0008 (glyS)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0008
|
| Name |
glyS
|
| Replicon | chromosome |
| Genomic location | 10434 - 12488 (- strand) |
Cross-References
| RefSeq | NP_064728.1 |
| GI | 15595206 |
| Affymetrix | PA0008_glyS_at |
| Entrez | 878214 |
| GenBank | AAG03398.1 |
| INSDC | AAG03398.1 |
| NCBI Locus Tag | PA0008 |
| protein_id(GenBank) | gb|AAG03398.1|AE004440_8|gnl|PseudoCAP|PA0008 |
| TIGR | NTL03PA00009 |
| UniParc | UPI00001364A2 |
| UniProtKB Acc | Q9I7B8 |
| UniProtKB ID | SYGB_PSEAE |
| UniRef100 | UniRef100_Q9I7B8 |
| UniRef50 | UniRef50_Q4KKR8 |
| UniRef90 | UniRef90_Q9I7B8 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
glycyl-tRNA synthetase beta chain
|
| Synonyms | |
| Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | -15.14 |
| Kyte-Doolittle Hydrophobicity Value | -0.032 |
| Molecular Weight (kDa) | 74.0 |
| Isoelectric Point (pI) | 4.84 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 403 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000008 (555 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0008
Search term: glyS
Search term: glycyl-tRNA synthetase beta chain
|
Human Homologs
References
|
Gene for Escherichia coli glycyl-tRNA synthetase has tandem subunit coding regions in the same reading frame.
Keng T, Webster TA, Sauer RT, Schimmel P
J Biol Chem 1982 Nov 10;257(21):12503-8
PubMed ID: 6290471
|
|
Primary structures of both subunits of Escherichia coli glycyl-tRNA synthetase.
Webster TA, Gibson BW, Keng T, Biemann K, Schimmel P
J Biol Chem 1983 Sep 10;258(17):10637-41
PubMed ID: 6309809
|
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|