Pseudomonas aeruginosa PAO1, PA0223 (ergB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0223
|
| Name |
ergB
|
| Replicon | chromosome |
| Genomic location | 252913 - 253794 (- strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 5 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248914.1 |
| GI | 15595420 |
| Affymetrix | PA0223_at |
| DNASU | PaCD00006099 |
| Entrez | 878110 |
| GenBank | AAG03612.1 |
| INSDC | AAG03612.1 |
| NCBI Locus Tag | PA0223 |
| protein_id(GenBank) | gb|AAG03612.1|AE004460_5|gnl|PseudoCAP|PA0223 |
| TIGR | NTL03PA00224 |
| UniParc | UPI00000C4FA6 |
| UniProtKB Acc | Q9I6R5 |
| UniProtKB ID | Q9I6R5_PSEAE |
| UniRef100 | UniRef100_W0YJN3 |
| UniRef50 | UniRef50_A0A0A1FXC1 |
| UniRef90 | UniRef90_B7V2D6 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
ErgB
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -5.89 |
| Kyte-Doolittle Hydrophobicity Value | 0.147 |
| Molecular Weight (kDa) | 31.7 |
| Isoelectric Point (pI) | 5.17 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 3NA8 | LYASE | 06/01/10 | Crystal Structure of a putative dihydrodipicolinate synthetase from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 1.85 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 633 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000222 (1168 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0223
Search term: ergB
Search term: ErgB
|
Human Homologs
References
|
Species-specific recruitment of transcription factors dictates toxin expression.
Trouillon J, Sentausa E, Ragno M, Robert-Genthon M, Lory S, Attrée I, Elsen S
Nucleic Acids Res 2020 Mar 18;48(5):2388-2400
PubMed ID: 31925438
|