Pseudomonas aeruginosa UCBPP-PA14, PA14_10250 (acoB)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_10250
Name	acoB
Replicon	chromosome
Genomic location	882259 - 883278 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_788969.1
GI	116052187
Entrez	4382160
INSDC	ABJ13423.1
NCBI Locus Tag	PA14_10250
UniParc	UPI00003962BC
UniProtKB Acc	Q02SW7
UniProtKB ID	Q02SW7_PSEAB
UniRef100	UniRef100_Q02SW7
UniRef50	UniRef50_Q4KEQ5
UniRef90	UniRef90_A0A067A575

Product

Feature Type	CDS
Coding Frame	1
Product Name	acetoin catabolism protein AcoB
Synonyms
Evidence for Translation
Charge (pH 7)	-11.52
Kyte-Doolittle Hydrophobicity Value	0.059
Molecular Weight (kDa)	36.4
Isoelectric Point (pI)	4.79

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 578 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001549 (405 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_10250 Search term: acoB Search term: acetoin catabolism protein AcoB

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000373220 pyruvate dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:8808] E-value: 1.0e-64 Percent Identity: 40.1

References