Pseudomonas aeruginosa UCBPP-PA14, PA14_14080

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_14080
Name
Replicon chromosome
Genomic location 1206731 - 1207378 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_789267.1
GI 116051890
Entrez 4385347
INSDC ABJ13126.1
NCBI Locus Tag PA14_14080
UniParc UPI00003961E8
UniProtKB Acc Q02S19
UniProtKB ID Q02S19_PSEAB
UniRef100 UniRef100_Q02S19
UniRef50 UniRef50_Q53547
UniRef90 UniRef90_Q9HXE7

Product

Feature Type CDS
Coding Frame 1
Product Name
carboxylesterase
Synonyms
Evidence for Translation
Charge (pH 7) -9.87
Kyte-Doolittle Hydrophobicity Value 0.027
Molecular Weight (kDa) 23.4
Isoelectric Point (pI) 4.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3CN9 HYDROLASE 03/25/08 Crystal Structure Analysis of the Carboxylesterase PA3859 from Pseudomonas aeruginosa PAO1- orthorhombic crystal form Pseudomonas aeruginosa 2.09 X-RAY DIFFRACTION 99.5
3CN7 HYDROLASE 03/25/08 Crystal Structure Analysis of the Carboxylesterase PA3859 from Pseudomonas aeruginosa PAO1- MONOCLINIC CRYSTAL FORM Pseudomonas aeruginosa 2.99 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 212 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001810 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_14080
Search term: carboxylesterase

Human Homologs

Ensembl 110, assembly GRCh38.p14
lysophospholipase 2 [Source:HGNC Symbol;Acc:HGNC:6738]
E-value: 1.0e-25
Percent Identity: 34.8

References

No references are associated with this feature.