Pseudomonas aeruginosa UCBPP-PA14, PA14_18470 (algL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_18470
Name
algL
Replicon chromosome
Genomic location 1584016 - 1585119 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_789618.1
GI 116051545
EC Number 4.2.2.3
Entrez 4381511
INSDC ABJ12781.1
NCBI Locus Tag PA14_18470
UniParc UPI0000125852
UniProtKB Acc Q02R18
UniProtKB ID ALGL_PSEAB
UniRef100 UniRef100_Q02R18
UniRef50 UniRef50_Q9L7P2
UniRef90 UniRef90_Q02R18

Product

Feature Type CDS
Coding Frame 1
Product Name
poly(beta-D-mannuronate) lyase
Synonyms
Evidence for Translation
Charge (pH 7) 5.33
Kyte-Doolittle Hydrophobicity Value -0.449
Molecular Weight (kDa) 40.8
Isoelectric Point (pI) 8.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7SA8 LYASE 09/22/21 Crystal Structure of the periplasmic lyase AlgL K66A Mutant Pseudomonas aeruginosa 2.5 X-RAY DIFFRACTION 99.7
4OZW LYASE 02/19/14 Crystal Structure of the periplasmic alginate lyase AlgL H202A mutant Pseudomonas aeruginosa 1.64 X-RAY DIFFRACTION 99.7
4OZV LYASE 02/19/14 Crystal Structure of the periplasmic alginate lyase AlgL Pseudomonas aeruginosa 1.642 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 12 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002119 (490 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_18470
Search term: algL

Human Homologs

References

No references are associated with this feature.