Pseudomonas aeruginosa UCBPP-PA14, PA14_18550 (alg44)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_18550
Name	alg44
Replicon	chromosome
Genomic location	1591122 - 1592291 (- strand)
Transposon Mutants	2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_789623.1
GI	116051540
Entrez	4381506
INSDC	ABJ12776.1
NCBI Locus Tag	PA14_18550
UniParc	UPI00000C5A60
UniProtKB Acc	Q02R13
UniProtKB ID	Q02R13_PSEAB
UniRef100	UniRef100_Q9HY69
UniRef50	UniRef50_Q9HY69
UniRef90	UniRef90_Q9HY69

Product

Feature Type	CDS
Coding Frame	1
Product Name	alginate biosynthesis protein Alg44
Synonyms
Evidence for Translation
Charge (pH 7)	5.63
Kyte-Doolittle Hydrophobicity Value	-0.067
Molecular Weight (kDa)	41.8
Isoelectric Point (pI)	9.29

Subcellular localization

Individual Mappings	Localization Confidence PMID Periplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4XRN	UNKNOWN FUNCTION	01/21/15	Pilz domain with c-di-gmp of a protein from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	99.1
4RT1	PROTEIN BINDING	11/12/14	Structure of the Alg44 PilZ domain (R95A mutant) from Pseudomonas aeruginosa PAO1 in complex with c-di-GMP	Pseudomonas aeruginosa	1.7	X-RAY DIFFRACTION	98.2
4RT0	PROTEIN BINDING	11/12/14	Structure of the Alg44 PilZ domain from Pseudomonas aeruginosa PAO1 in complex with c-di-GMP	Pseudomonas aeruginosa	1.8	X-RAY DIFFRACTION	99.1

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002124 (491 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_18550 Search term: alg44 Search term: alginate biosynthesis protein Alg44

Human Homologs

References