Pseudomonas aeruginosa UCBPP-PA14, PA14_21820

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_21820
Name
Replicon chromosome
Genomic location 1896757 - 1897518 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_789892.1
GI 116051276
Entrez 4381261
INSDC ABJ12512.1
NCBI Locus Tag PA14_21820
UniParc UPI00000C597F
UniProtKB Acc Q02Q94
UniProtKB ID Q02Q94_PSEAB
UniRef100 UniRef100_W0YVN7
UniRef50 UniRef50_A4VN69
UniRef90 UniRef90_A6V2F7

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidyl-prolyl cis-trans isomerase, FkbP-type
Synonyms
Evidence for Translation
Charge (pH 7) -7.30
Kyte-Doolittle Hydrophobicity Value -0.348
Molecular Weight (kDa) 26.8
Isoelectric Point (pI) 4.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7DEK ISOMERASE 11/04/20 Pseudomonas aeruginosa FK506-binding protein PaFkbA Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.9 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 398 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002348 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_21820

Human Homologs

Ensembl 110, assembly GRCh38.p14
FKBP prolyl isomerase 1A [Source:HGNC Symbol;Acc:HGNC:3711]
E-value: 3.6e-14
Percent Identity: 42.1
Ensembl 110, assembly GRCh38.p14
FKBP prolyl isomerase 1A [Source:HGNC Symbol;Acc:HGNC:3711]
E-value: 3.6e-14
Percent Identity: 42.1
Ensembl 110, assembly GRCh38.p14
FKBP prolyl isomerase 1A [Source:HGNC Symbol;Acc:HGNC:3711]
E-value: 3.6e-14
Percent Identity: 42.1
Ensembl 110, assembly GRCh38.p14
FKBP prolyl isomerase 1A [Source:HGNC Symbol;Acc:HGNC:3711]
E-value: 3.6e-14
Percent Identity: 42.1
Ensembl 110, assembly GRCh38.p14
FKBP prolyl isomerase 1A [Source:HGNC Symbol;Acc:HGNC:3711]
E-value: 3.6e-14
Percent Identity: 42.1

References

No references are associated with this feature.