Pseudomonas aeruginosa UCBPP-PA14, PA14_22620 (cyaB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_22620
Name
cyaB
Replicon chromosome
Genomic location 1966871 - 1968262 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_789962.1
GI 116051207
Entrez 4383116
INSDC ABJ12443.1
NCBI Locus Tag PA14_22620
UniParc UPI0000E449BA
UniProtKB Acc Q02Q24
UniProtKB ID Q02Q24_PSEAB
UniRef100 UniRef100_Q02Q24
UniRef50 UniRef50_Q9HZ23
UniRef90 UniRef90_Q9HZ23

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Charge (pH 7) 12.71
Kyte-Doolittle Hydrophobicity Value 0.126
Molecular Weight (kDa) 51.4
Isoelectric Point (pI) 9.38

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3R5G LYASE 03/18/11 Crystal structure of the adenylyl cyclase CyaB from P. aeruginosa Pseudomonas aeruginosa 1.5 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 257 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002398 (355 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_22620
Search term: cyaB

Human Homologs

Ensembl 110, assembly GRCh38.p14
guanylate cyclase 2F, retinal [Source:HGNC Symbol;Acc:HGNC:4691]
E-value: 6.8e-11
Percent Identity: 27.5

References

No references are associated with this feature.