Pseudomonas aeruginosa UCBPP-PA14, PA14_23070 (zwf)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_23070
Name	zwf
Replicon	chromosome
Genomic location	2000159 - 2001628 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_789997.1
GI	116051172
EC Number	1.1.1.49
Entrez	4381176
INSDC	ABJ12408.1
NCBI Locus Tag	PA14_23070
UniParc	UPI0000E449C1
UniProtKB Acc	Q02PY9
UniProtKB ID	Q02PY9_PSEAB
UniRef100	UniRef100_Q02PY9
UniRef50	UniRef50_O68282
UniRef90	UniRef90_O68282

Product

Feature Type	CDS
Coding Frame	1
Product Name	glucose-6-phosphate 1-dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-8.45
Kyte-Doolittle Hydrophobicity Value	-0.267
Molecular Weight (kDa)	55.6
Isoelectric Point (pI)	5.68

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 391 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002433 (530 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_23070 Search term: zwf Search term: glucose-6-phosphate 1-dehydrogenase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000377194 glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] E-value: 9.2e-83 Percent Identity: 36.1
Ensembl 110, assembly GRCh38.p14	ENSP00000377192 glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] E-value: 9.2e-83 Percent Identity: 36.1
Ensembl 110, assembly GRCh38.p14	ENSP00000512625 glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] E-value: 9.2e-83 Percent Identity: 36.1
Ensembl 110, assembly GRCh38.p14	ENSP00000512624 glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] E-value: 9.2e-83 Percent Identity: 36.1

References