Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_23590
|
Name |
sawR
|
Replicon | chromosome |
Genomic location | 2053723 - 2054265 (+ strand) |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | SawR down-regulates the expression levels of hmgA and this causes the accumulation of the brown pigment pyomelanin. Note that SawR does not bind directly to the hmgA promoter. |
Comment | sawR is highly overexpressed when P. aeruginosa is exposed to Surface Acoustic Waves. |
RefSeq | YP_790040.1 |
GI | 116051129 |
Entrez | 4381133 |
INSDC | ABJ12365.1 |
NCBI Locus Tag | PA14_23590 |
UniParc | UPI0000395FCF |
UniProtKB Acc | Q02PU6 |
UniProtKB ID | Q02PU6_PSEAB |
UniRef100 | UniRef100_W0YVB7 |
UniRef50 | UniRef50_Q9HZ91 |
UniRef90 | UniRef90_Q9HZ91 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
SawR
|
Synonyms |
transcriptional regulator |
Evidence for Translation | |
Charge (pH 7) | -1.31 |
Kyte-Doolittle Hydrophobicity Value | 0.022 |
Molecular Weight (kDa) | 19.1 |
Isoelectric Point (pI) | 6.28 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2FD5 | TRANSCRIPTION REGULATOR | 12/13/05 | The crystal structure of a transcriptional regulator from Pseudomonas aeruginosa PAO1 | Pseudomonas aeruginosa | 1.7 | X-RAY DIFFRACTION | 99.4 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 158 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002465 (448 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_23590
Search term: sawR
Search term: SawR
|
Surface acoustic waves increase the susceptibility of Pseudomonas aeruginosa biofilms to antibiotic treatment.
Kopel M, Degtyar E, Banin E
Biofouling 2011 Aug;27(7):701-10
PubMed ID: 21732715
|
SawR a new regulator controlling pyomelanin synthesis in Pseudomonas aeruginosa.
Ben-David Y, Zlotnik E, Zander I, Yerushalmi G, Shoshani S, Banin E
Microbiol Res 2018 Jan;206:91-98
PubMed ID: 29146265
|