Pseudomonas aeruginosa UCBPP-PA14, PA14_23650

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_23650
Name
Replicon chromosome
Genomic location 2057398 - 2058144 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_790045.1
GI 116051124
Entrez 4381128
INSDC ABJ12360.1
NCBI Locus Tag PA14_23650
UniParc UPI0000395FCA
UniProtKB Acc Q02PU1
UniProtKB ID Q02PU1_PSEAB
UniRef100 UniRef100_S0I2Y0
UniRef50 UniRef50_Q12GY8
UniRef90 UniRef90_A0A086BZR1

Product

Feature Type CDS
Coding Frame 1
Product Name
short chain dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -1.06
Kyte-Doolittle Hydrophobicity Value -0.052
Molecular Weight (kDa) 26.2
Isoelectric Point (pI) 6.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
8BCJ UNKNOWN FUNCTION 10/16/22 Crystal structure of short-chain dehydrogenase PA3128 from Pseudomonas aeruginosa PAO1 in complex with NADP+ Pseudomonas aeruginosa PAO1 1.15 X-RAY DIFFRACTION 99.2
8BCI UNKNOWN FUNCTION 10/16/22 Crystal structure of short-chain dehydrogenase PA3128 from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 1.7 X-RAY DIFFRACTION 99.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002470 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_23650

Human Homologs

Ensembl 110, assembly GRCh38.p14
carbonyl reductase 4 [Source:HGNC Symbol;Acc:HGNC:25891]
E-value: 8.6e-29
Percent Identity: 38.2

References

No references are associated with this feature.