Pseudomonas aeruginosa UCBPP-PA14, PA14_23880 (folC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_23880
Name
folC
Replicon chromosome
Genomic location 2075598 - 2076887 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_790062.1
GI 116051107
Entrez 4381111
INSDC ABJ12343.1
NCBI Locus Tag PA14_23880
UniParc UPI0000395FBF
UniProtKB Acc Q02PS4
UniProtKB ID Q02PS4_PSEAB
UniRef100 UniRef100_Q02PS4
UniRef50 UniRef50_Q4KEZ7
UniRef90 UniRef90_A0A022P9Z5

Product

Feature Type CDS
Coding Frame 1
Product Name
folylpolyglutamate synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -13.42
Kyte-Doolittle Hydrophobicity Value -0.007
Molecular Weight (kDa) 46.6
Isoelectric Point (pI) 4.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 604 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002487 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_23880
Search term: folC

Human Homologs

Ensembl 110, assembly GRCh38.p14
folylpolyglutamate synthase [Source:HGNC Symbol;Acc:HGNC:3824]
E-value: 1.5e-25
Percent Identity: 39.3
Ensembl 110, assembly GRCh38.p14
folylpolyglutamate synthase [Source:HGNC Symbol;Acc:HGNC:3824]
E-value: 1.5e-25
Percent Identity: 39.3

References

No references are associated with this feature.