Pseudomonas aeruginosa UCBPP-PA14, PA14_23970 (xcpQ)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_23970
Name	xcpQ
Replicon	chromosome
Genomic location	2081960 - 2083936 (- strand)
Transposon Mutants	3 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	18 transposon mutants in orthologs

Cross-References

RefSeq	YP_790068.1
GI	116051101
Entrez	4381105
INSDC	ABJ12337.1
NCBI Locus Tag	PA14_23970
UniParc	UPI0000395FBB
UniProtKB Acc	Q02PR8
UniProtKB ID	Q02PR8_PSEAB
UniRef100	UniRef100_Q02PR8
UniRef50	UniRef50_P35818
UniRef90	UniRef90_P35818

Product

Feature Type	CDS
Coding Frame	1
Product Name	general secretion pathway protein D
Synonyms
Evidence for Translation
Charge (pH 7)	-4.04
Kyte-Doolittle Hydrophobicity Value	-0.134
Molecular Weight (kDa)	70.0
Isoelectric Point (pI)	6.15

Subcellular localization

Individual Mappings	Localization Confidence PMID Outer Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4EC5	PROTEIN TRANSPORT	03/26/12	Crystal structure of the S210C (dimer) mutant from the N-terminal domain of the secretin XcpQ from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2.197	X-RAY DIFFRACTION	98.8
5MP2	TRANSPORT PROTEIN	12/15/16	XcpQN012 in complex with VHH04	Lama glama; Pseudomonas aeruginosa	2.9	X-RAY DIFFRACTION	100.0
5NGI	TRANSPORT PROTEIN	03/17/17	Structure of XcpQN012	Pseudomonas aeruginosa	2.98	X-RAY DIFFRACTION	100.0
5WLN	MEMBRANE PROTEIN	07/27/17	Cryo-EM structure of the T2SS secretin XcpQ from Pseudomonas aeruginosa	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	3.57	ELECTRON MICROSCOPY	99.7
4E9J	PROTEIN TRANSPORT	03/21/12	Crystal structure of the N-terminal domain of the secretin XcpQ from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2.03	X-RAY DIFFRACTION	99.2

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 347 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000664 (1798 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_23970 Search term: xcpQ Search term: general secretion pathway protein D

Human Homologs

References