Pseudomonas aeruginosa UCBPP-PA14, PA14_24050 (xcpV)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_24050
Name	xcpV
Replicon	chromosome
Genomic location	2088566 - 2088955 (+ strand)
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_790074.1
GI	116051095
Entrez	4381099
INSDC	ABJ12331.1
NCBI Locus Tag	PA14_24050
UniParc	UPI0000395FB7
UniProtKB Acc	Q02PR2
UniProtKB ID	Q02PR2_PSEAB
UniRef100	UniRef100_Q02PR2
UniRef50	UniRef50_Q00516
UniRef90	UniRef90_Q00516

Product

Feature Type	CDS
Coding Frame	1
Product Name	general secretion pathway protein I
Synonyms
Evidence for Translation
Charge (pH 7)	2.99
Kyte-Doolittle Hydrophobicity Value	-0.244
Molecular Weight (kDa)	14.4
Isoelectric Point (pI)	11.12

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6UTU	PROTEIN TRANSPORT	10/30/19	Crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa in the P3 space group	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	2.85	X-RAY DIFFRACTION	100.0
5VTM	TRANSPORT PROTEIN	05/17/17	The crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	2.041	X-RAY DIFFRACTION	100.0
5BW0	PROTEIN TRANSPORT	06/05/15	The crystal structure of minor pseudopilin binary complex of XcpV and XcpW from the Type 2 secretion system of Pseudomonas aeruginosa	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 91 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002495 (370 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_24050 Search term: xcpV Search term: general secretion pathway protein I

Human Homologs

References