Pseudomonas aeruginosa UCBPP-PA14, PA14_25530 (kdsB)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_25530
Name	kdsB
Replicon	chromosome
Genomic location	2230872 - 2231636 (+ strand)

Cross-References

RefSeq	YP_790194.1
GI	116050981
EC Number	2.7.7.38
Entrez	4381005
INSDC	ABJ12217.1
NCBI Locus Tag	PA14_25530
UniParc	UPI0000395F62
UniProtKB Acc	Q02PE2
UniProtKB ID	KDSB_PSEAB
UniRef100	UniRef100_Q02PE2
UniRef50	UniRef50_P44490
UniRef90	UniRef90_Q9HZM5

Product

Feature Type	CDS
Coding Frame	1
Product Name	3-deoxy-manno-octulosonate cytidylyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-6.61
Kyte-Doolittle Hydrophobicity Value	-0.037
Molecular Weight (kDa)	27.7
Isoelectric Point (pI)	5.15

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4XWI	TRANSFERASE	01/28/15	X-ray Crystal structure of CMP-KDO Synthase from Pseudomonas aeruginosa	Pseudomonas aeruginosa	1.92	X-RAY DIFFRACTION	99.6

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 374 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002603 (534 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_25530 Search term: kdsB Search term: 3-deoxy-manno-octulosonate cytidylyltransferase

Human Homologs

References