Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4132
|
Name |
mpaR
|
Replicon | chromosome |
Genomic location | 4621133 - 4622548 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | Deletion of mpaR caused increased biofilm formation, but reduced pyocyanin production (PMID:32748556) |
Comment | Deletion of mpaR leads to increased expression of the ant operon and the catechol production (PMID:32748556) |
RefSeq | NP_252821.1 |
GI | 15599327 |
Affymetrix | PA4132_at |
Entrez | 880050 |
GenBank | AAG07519.1 |
INSDC | AAG07519.1 |
NCBI Locus Tag | PA4132 |
protein_id(GenBank) | gb|AAG07519.1|AE004829_9|gnl|PseudoCAP|PA4132 |
TIGR | NTL03PA04132 |
UniParc | UPI00000C5C29 |
UniProtKB Acc | Q9HWP9 |
UniProtKB ID | Q9HWP9_PSEAE |
UniRef100 | UniRef100_Q9HWP9 |
UniRef50 | UniRef50_Q4KCQ9 |
UniRef90 | UniRef90_Q9HWP9 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
MpaR
|
Synonyms |
MvfR-mediated PQS and anthranilate regulator |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 4.50 |
Kyte-Doolittle Hydrophobicity Value | -0.099 |
Molecular Weight (kDa) | 52.3 |
Isoelectric Point (pI) | 8.20 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 617 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001567 (527 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4132
Search term: mpaR
Search term: MpaR
|
A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.
Aiba H, Baba T, Hayashi K, Inada T, Isono K, Itoh T, Kasai H, Kashimoto K, Kimura S, Kitakawa M, Kitagawa M, Makino K, Miki T, Mizobuchi K, Mori H, Mori T, Motomura K, Nakade S, Nakamura Y, Nashimoto H, Nishio Y, Oshima T, Saito N, Sampei G, Horiuchi T
DNA Res 1996 Dec 31;3(6):363-77
PubMed ID: 9097039
|
A novel cyanide-inducible gene cluster helps protect Pseudomonas aeruginosa from cyanide.
Frangipani E, Pérez-Martínez I, Williams HD, Cherbuin G, Haas D
Environ Microbiol Rep 2014 Feb;6(1):28-34
PubMed ID: 24596260
|
Coordinated regulation of anthranilate metabolism and bacterial virulence by the GntR family regulator MpaR in Pseudomonas aeruginosa.
Wang T, Qi Y, Wang Z, Zhao J, Ji L, Li J, Cai Z, Yang L, Wu M, Liang H
Mol Microbiol 2020 Nov;114(5):857-869
PubMed ID: 32748556
|