Pseudomonas aeruginosa UCBPP-PA14, PA14_01100 (clpV1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_01100
Name
clpV1
Replicon chromosome
Genomic location 105874 - 108582 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 6 transposon mutants in orthologs
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)

Cross-References

RefSeq YP_788247.1
GI 116053810
Entrez 4383508
INSDC ABJ15046.1
NCBI Locus Tag PA14_01100
UniParc UPI0000396C20
UniProtKB Acc Q02UY9
UniProtKB ID Q02UY9_PSEAB
UniRef100 UniRef100_S0HSC8
UniRef50 UniRef50_Q9I742
UniRef90 UniRef90_Q9I742

Product

Feature Type CDS
Coding Frame 1
Product Name
ClpV1
Product Name Confidence: Class 1
Synonyms ClpA/B-type chaperone
Evidence for Translation
Charge (pH 7) -21.22
Kyte-Doolittle Hydrophobicity Value -0.161
Molecular Weight (kDa) 98.7
Isoelectric Point (pI) 5.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 597 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000089 (1168 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01100
Search term: clpV1
Search term: ClpV1

Human Homologs

References

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999
Coevolution of the ATPase ClpV, the sheath proteins TssB and TssC, and the accessory protein TagJ/HsiE1 distinguishes type VI secretion classes.
Förster A, Planamente S, Manoli E, Lossi NS, Freemont PS, Filloux A
J Biol Chem 2014 Nov 21;289(47):33032-43
PubMed ID: 25305017