Pseudomonas aeruginosa UCBPP-PA14, PA14_43720 (bosR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_43720
Name
bosR
Synonym: one-component transcriptional regulator
Replicon chromosome
Genomic location 3893718 - 3894158 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_791644.1
GI 116049552
Entrez 4381760
INSDC ABJ10788.1
NCBI Locus Tag PA14_43720
UniParc UPI00000C5405
UniProtKB Acc Q02K92
UniProtKB ID Q02K92_PSEAB
UniRef100 UniRef100_W0YQ96
UniRef50 UniRef50_W7P8X5
UniRef90 UniRef90_A6V7I6

Product

Feature Type CDS
Coding Frame 1
Product Name
biofilm oxidative stress regulator, BosR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 1.92
Kyte-Doolittle Hydrophobicity Value -0.295
Molecular Weight (kDa) 16.2
Isoelectric Point (pI) 8.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2F2E DNA BINDING PROTEIN/STRUCTURAL GENOMICS 11/16/05 Crystal Structure of PA1607, a Putative Transcription Factor Pseudomonas aeruginosa 1.85 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 357 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000114 (1395 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_43720
Search term: bosR

Human Homologs

References

BosR: A novel biofilm-specific regulator in Pseudomonas aeruginosa.
Dostert M, Belanger CR, Pedraz L, Alford MA, Blimkie TM, Falsafi RF, Bains M, Dhillon BK, Haney CH, Lee AH, Hancock REW
Front Microbiol 2022;13:1021021
PubMed ID: 36312952