Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0778
|
Name |
icp
|
Replicon | chromosome |
Genomic location | 845278 - 845682 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_249469.1 |
GI | 15595975 |
Affymetrix | PA0778_at |
DNASU | PaCD00006356 |
Entrez | 879252 |
GenBank | AAG04167.1 |
INSDC | AAG04167.1 |
NCBI Locus Tag | PA0778 |
protein_id(GenBank) | gb|AAG04167.1|AE004512_10|gnl|PseudoCAP|PA0778 |
TIGR | NTL03PA00779 |
UniParc | UPI00000C5148 |
UniProtKB Acc | Q9I5G0 |
UniProtKB ID | Q9I5G0_PSEAE |
UniRef100 | UniRef100_Q9I5G0 |
UniRef50 | UniRef50_Q9I5G0 |
UniRef90 | UniRef90_Q9I5G0 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
inhibitor of cysteine peptidase
|
Synonyms |
chagasin-like protein |
Evidence for Translation | |
Charge (pH 7) | -4.10 |
Kyte-Doolittle Hydrophobicity Value | -0.259 |
Molecular Weight (kDa) | 14.6 |
Isoelectric Point (pI) | 4.58 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2WGN | HYDROLASE INHIBITOR | 04/21/09 | Pseudomonas aeruginosa ICP | PSEUDOMONAS AERUGINOSA | NOT | SOLUTION NMR | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 39 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000752 (523 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0778
Search term: icp
Search term: inhibitor of cysteine peptidase
|
Functional conservation of a natural cysteine peptidase inhibitor in protozoan and bacterial pathogens.
Sanderson SJ, Westrop GD, Scharfstein J, Mottram JC, Coombs GH
FEBS Lett 2003 May 8;542(1-3):12-6
PubMed ID: 12729889
|
Sequence conservation in the chagasin family suggests a common trend in cysteine proteinase binding by unrelated protein inhibitors.
Rigden DJ, Mosolov VV, Galperin MY
Protein Sci 2002 Aug;11(8):1971-7
PubMed ID: 12142451
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|