Pseudomonas aeruginosa PAO1, PA2852 (earP)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA2852
Name	earP
Replicon	chromosome
Genomic location	3205123 - 3206253 (- strand)
Transposon Mutants	1 transposon mutants in PAO1
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	NP_251542.1
GI	15598048
Affymetrix	PA2852_at
Entrez	882634
GenBank	AAG06240.1
INSDC	AAG06240.1
NCBI Locus Tag	PA2852
protein_id(GenBank)	gb|AAG06240.1|AE004711_12|gnl|PseudoCAP|PA2852
TIGR	NTL03PA02852
UniParc	UPI00000C5844
UniProtKB Acc	Q9HZZ1
UniProtKB ID	Q9HZZ1_PSEAE
UniRef100	UniRef100_Q9HZZ1
UniRef50	UniRef50_Q9HZZ1
UniRef90	UniRef90_Q9HZZ1

Product

Feature Type	CDS
Coding Frame	1
Product Name	EarP Product Name Confidence: Class 1
Synonyms	hypothetical protein
Evidence for Translation
Charge (pH 7)	-8.57
Kyte-Doolittle Hydrophobicity Value	-0.152
Molecular Weight (kDa)	42.8
Isoelectric Point (pI)	5.19

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6J7K	TRANSFERASE	01/18/19	Crystal structure of Pseudomonas aeruginosa Earp in complex with TDP-Rha	Pseudomonas aeruginosa PAO1	2.15	X-RAY DIFFRACTION	100.0
6J7L	TRANSFERASE	01/18/19	Crystal structure of Pseudomonas aeruginosa Earp in complex with TDP	Pseudomonas aeruginosa PAO1	1.851	X-RAY DIFFRACTION	100.0
6J7M	TRANSFERASE	01/18/19	Complex structure of the Pseudomonas aeruginosa rhamnosyltransferase EarP with the acceptor elongation factor EF-P	Pseudomonas aeruginosa PAO1	2.301	X-RAY DIFFRACTION	100.0
6J7J	TRANSFERASE	01/18/19	Crystal structure of Pseudomonas aeruginosa Earp	Pseudomonas aeruginosa PAO1	1.75	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 60 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002716 (532 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2852 Search term: earP Search term: EarP

Human Homologs

References