Pseudomonas aeruginosa PAO1, PA3477 (rhlR)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0045862	positive regulation of proteolysis	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	8522523	Reviewed by curator
Biological Process	GO:0050896	response to stimulus	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006355	regulation of transcription, DNA-templated	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	8144472	Reviewed by curator
Biological Process	GO:1900378	positive regulation of secondary metabolite biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	8522523	Reviewed by curator
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:cd06170	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF46894	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02024	Quorum sensing	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR44688	-	-	-	29	240	2.3E-19
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	211	223	2.1E-11
SUPERFAMILY	SSF75516	Pheromone-binding domain of LuxR-like quorum-sensing transcription factors	IPR036693	Transcription factor LuxR-like, autoinducer-binding domain superfamily	9	172	3.79E-39
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	181	195	2.1E-11
SUPERFAMILY	SSF46894	C-terminal effector domain of the bipartite response regulators	IPR016032	Signal transduction response regulator, C-terminal effector	171	241	3.74E-18
SMART	SM00421	luxrmega5	IPR000792	Transcription regulator LuxR, C-terminal	178	235	8.9E-20
FunFam	G3DSA:1.10.10.10:FF:000297	DNA-binding transcriptional activator SdiA	-	-	178	241	3.8E-35
Pfam	PF00196	Bacterial regulatory proteins, luxR family	IPR000792	Transcription regulator LuxR, C-terminal	181	235	2.0E-19
Gene3D	G3DSA:1.10.10.10	-	IPR036388	Winged helix-like DNA-binding domain superfamily	180	241	4.2E-20
Pfam	PF03472	Autoinducer binding domain	IPR005143	Transcription factor LuxR-like, autoinducer-binding domain	26	164	8.3E-36
Gene3D	G3DSA:3.30.450.80	-	IPR036693	Transcription factor LuxR-like, autoinducer-binding domain superfamily	3	177	7.9E-47
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	195	211	2.1E-11
CDD	cd06170	LuxR_C_like	IPR000792	Transcription regulator LuxR, C-terminal	181	229	2.72453E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.