Pseudomonas aeruginosa PAO1, PA3947 (rocR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 15659157 Reviewed by curator
Molecular Function GO:0071111 cyclic-guanylate-specific phosphodiesterase activity
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 16477007 Reviewed by curator
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00563 EAL domain IPR001633 EAL domain 146 379 4.0E-63
CDD cd01948 EAL IPR001633 EAL domain 145 384 6.74857E-93
Gene3D G3DSA:3.20.20.450 EAL domain IPR035919 EAL domain superfamily 141 391 2.8E-83
CDD cd17530 REC_RocR - - 4 127 6.50268E-54
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 6 120 4.3E-11
Gene3D G3DSA:3.40.50.2300 - - - 1 139 2.8E-28
PANTHER PTHR33121 CYCLIC DI-GMP PHOSPHODIESTERASE PDEF - - 17 388 1.7E-82
SMART SM00052 duf2_2 IPR001633 EAL domain 139 384 2.7E-70
SUPERFAMILY SSF141868 EAL domain-like IPR035919 EAL domain superfamily 146 389 1.03E-72
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1 182 6.55E-21
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 4 122 1.2E-9

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.