Pseudomonas aeruginosa PAO1, PA3948 (rocA1)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0000156	phosphorelay response regulator activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	15659157	Reviewed by curator
Biological Process	GO:0045893	positive regulation of transcription, DNA-templated	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	15659157	Reviewed by curator
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00448	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:cd06170	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF46894	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Two-component System		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
CDD	cd17535	REC_NarL-like	-	-	4	117	3.93645E-44
Pfam	PF00072	Response regulator receiver domain	IPR001789	Signal transduction response regulator, receiver domain	4	115	1.2E-30
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	162	178	1.1E-10
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	148	162	1.1E-10
PANTHER	PTHR43214	TWO-COMPONENT RESPONSE REGULATOR	IPR039420	Transcriptional regulatory protein WalR-like	4	206	4.3E-39
Pfam	PF00196	Bacterial regulatory proteins, luxR family	IPR000792	Transcription regulator LuxR, C-terminal	148	202	6.1E-18
SUPERFAMILY	SSF46894	C-terminal effector domain of the bipartite response regulators	IPR016032	Signal transduction response regulator, C-terminal effector	137	208	7.14E-18
SMART	SM00448	REC_2	IPR001789	Signal transduction response regulator, receiver domain	2	114	4.5E-32
SUPERFAMILY	SSF52172	CheY-like	IPR011006	CheY-like superfamily	1	128	5.98E-31
CDD	cd06170	LuxR_C_like	IPR000792	Transcription regulator LuxR, C-terminal	148	204	1.17203E-15
SMART	SM00421	luxrmega5	IPR000792	Transcription regulator LuxR, C-terminal	145	202	6.3E-20
Gene3D	G3DSA:1.10.10.10	-	IPR036388	Winged helix-like DNA-binding domain superfamily	138	207	2.8E-18
PRINTS	PR00038	LuxR bacterial regulatory protein HTH signature	IPR000792	Transcription regulator LuxR, C-terminal	178	190	1.1E-10
Gene3D	G3DSA:3.40.50.2300	-	-	-	2	128	1.7E-31

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.