Pseudomonas aeruginosa PAO1, PA4303 (tadZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4303
Name
tadZ
Synonym: tadZ
Replicon chromosome
Genomic location 4827185 - 4828369 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252993.1
GI 15599499
Affymetrix PA4303_at
Entrez 881617
GenBank AAG07691.1
INSDC AAG07691.1
NCBI Locus Tag PA4303
protein_id(GenBank) gb|AAG07691.1|AE004846_8|gnl|PseudoCAP|PA4303
TIGR NTL03PA04304
UniParc UPI00000C5CA8
UniProtKB Acc Q9HW97
UniProtKB ID Q9HW97_PSEAE
UniRef100 UniRef100_W0Z065
UniRef50 UniRef50_W0Z065
UniRef90 UniRef90_W0Z065

Product

Feature Type CDS
Coding Frame 1
Product Name
TadZ
Product Name Confidence: Class 2
Synonyms TadZ
Evidence for Translation
Charge (pH 7) 0.67
Kyte-Doolittle Hydrophobicity Value 0.175
Molecular Weight (kDa) 42.4
Isoelectric Point (pI) 7.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4LDA TRANSCRIPTION 06/24/13 Crystal structure of a CheY-like protein (tadZ) from Pseudomonas aeruginosa PAO1 at 2.70 A resolution Pseudomonas aeruginosa 2.4 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 82 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003904 (429 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4303
Search term: tadZ
Search term: TadZ

Human Homologs

References

FppA, a novel Pseudomonas aeruginosa prepilin peptidase involved in assembly of type IVb pili.
de Bentzmann S, Aurouze M, Ball G, Filloux A
J Bacteriol 2006 Jul;188(13):4851-60
PubMed ID: 16788194
Mutation analysis of the flp operon in Actinobacillus actinomycetemcomitans.
Wang Y, Chen C
Gene 2005 May 23;351:61-71
PubMed ID: 15837433